VAT1 antibody (AA 421-525) (Cy5.5)

Catalog No. ABIN719821

This Rabbit Polyclonal antibody specifically detects VAT1 in WB, IF (cc) and IF (p). It exhibits reactivity toward Rat and Mouse.

Quick Overview for VAT1 antibody (AA 421-525) (Cy5.5) (ABIN719821)

Target: VAT1 (Vesicle Amine Transport 1 (VAT1))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAT1 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-VAT1 Antibody (Cy5.5)

Binding Specificity: AA 421-525

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VMAT1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for VAT1

Target: VAT1 (Vesicle Amine Transport 1 (VAT1))

Alternative Name: VAT1

Background:

Synonyms: Adrenal chromaffin granule amine transporter, CGAT, CGAT, Chromaffin granule amine transporter, SLC18A1, Solute carrier family 18 vesicular monoamine, member 1, Solute carrier family 18 member 1, VAT 1, VAT1, Vesicular amine transporter 1, VMAT 1, VMAT1, VMAT1_HUMAN.

Background: The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008].

Gene ID: 6570

UniProt: P54219