PNPLA6 antibody (C-Term)

Catalog No. ABIN7467589

The Rabbit Polyclonal anti-PNPLA6 antibody has been validated for WB and IHC (p). It is suitable to detect PNPLA6 in samples from Human.

Quick Overview for PNPLA6 antibody (C-Term) (ABIN7467589)

Target: PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNPLA6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PNPLA6 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human NTE. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: U87-MG , SK-N-SH , IMR-32 , SK-N-AS , rat brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PNPLA6

Target: PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))

Alternative Name: patatin like phospholipase domain containing 6

Background: Patatin like phospholipase domain containing 6 , BNHS , LNMS , NTE , NTEMND , OMCS , SPG39 , iPLA2delta , sws,This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Molecular Weight: 150 kDa

Gene ID: 10908

UniProt: Q8IY17

Pathways: Ribonucleoside Biosynthetic Process