ATP6V0D1 antibody

Catalog No. ABIN7468016

This anti-ATP6V0D1 antibody is a Rabbit Polyclonal antibody detecting ATP6V0D1 in WB and IHC. Suitable for Human.

Quick Overview for ATP6V0D1 antibody (ABIN7468016)

Target: ATP6V0D1 (ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D1 (ATP6V0D1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V0D1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ATP6V0D1 Antibody

Cross-Reactivity: Human, Zebrafish (Danio rerio)

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ATP6V0D1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: IMR32

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ATP6V0D1

Target: ATP6V0D1 (ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D1 (ATP6V0D1))

Alternative Name: ATPase H+ transporting V0 subunit d1

Background:

Synonyms: ATPase H+ transporting V0 subunit d1 , ATP6D , ATP6DV , P39 , VATX , VMA6 , VPATPD

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously. [provided by RefSeq]

Molecular Weight: 40 kDa

Gene ID: 9114

UniProt: P61421

Pathways: Transition Metal Ion Homeostasis, Proton Transport, ER-Nucleus Signaling, Unfolded Protein Response