COQ8A antibody

Catalog No. ABIN7468153

The Rabbit Polyclonal anti-COQ8A antibody has been validated for WB, IF, ICC and IHC (p). It is suitable to detect COQ8A in samples from Human.

Quick Overview for COQ8A antibody (ABIN7468153)

Target: COQ8A (Coenzyme Q8A (COQ8A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COQ8A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-COQ8A Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CABC1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: IMR32 , Mouse heart

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.53 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for COQ8A

Target: COQ8A (Coenzyme Q8A (COQ8A))

Alternative Name: coenzyme Q8A

Background:

Synonyms: coenzyme Q8A , ADCK3 , ARCA2 , CABC1 , COQ10D4 , COQ8 , SCAR9

Background: This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found, however, their full-length nature has not been determined. [provided by RefSeq]

Molecular Weight: 72 kDa

Gene ID: 56997

UniProt: Q8NI60