FZD6 antibody
Quick Overview for FZD6 antibody (ABIN7468346)
Target
See all FZD6 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human
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Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human Frizzled 6. The exact sequence is proprietary.
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Validation: Orthogonal
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- FZD6 (Frizzled Family Receptor 6 (FZD6))
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Alternative Name
- frizzled class receptor 6
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Background
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Synonyms: frizzled class receptor 6 , FZ-6 , FZ6 , HFZ6 , NDNC10
Background: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD6 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and 7 transmembrane domains. However, unlike many other Fz family members, FDZ6 does not contain a C-terminal PDZ domain-binding motif. [provided by RefSeq]
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Molecular Weight
- 79 kDa
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Gene ID
- 8323
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UniProt
- O60353
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Pathways
- WNT Signaling, Tube Formation
Target
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