OPA1 antibody (C-Term)

Catalog No. ABIN7468694

This anti-OPA1 antibody is a Rabbit Polyclonal antibody detecting OPA1 in WB. Suitable for Human.

Quick Overview for OPA1 antibody (C-Term) (ABIN7468694)

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OPA1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human OPA1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.07 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for OPA1

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Alternative Name: OPA1 mitochondrial dynamin like GTPase

Background:

Synonyms: OPA1 mitochondrial dynamin like GTPase , BERHS , MGM1 , MTDPS14 , NPG , NTG , largeG

Background: This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Molecular Weight: 112 kDa

Gene ID: 4976

UniProt: O60313

Pathways: Tube Formation