P2RY11 antibody (C-Term)

Catalog No. ABIN7468834

The Rabbit Polyclonal anti-P2RY11 antibody has been validated for WB and IHC (fro). It is suitable to detect P2RY11 in samples from Human.

Quick Overview for P2RY11 antibody (C-Term) (ABIN7468834)

Target: P2RY11 (Purinergic Receptor P2Y, G-Protein Coupled, 11 (P2RY11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RY11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-P2RY11 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human P2Y11. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for P2RY11

Target: P2RY11 (Purinergic Receptor P2Y, G-Protein Coupled, 11 (P2RY11))

Alternative Name: purinergic receptor P2Y11

Background:

Synonyms: purinergic receptor P2Y11 , P2Y11

Background: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product. [provided by RefSeq]

Molecular Weight: 40 kDa

Gene ID: 5032

UniProt: Q96G91

Pathways: cAMP Metabolic Process