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TSG101 antibody (AA 167-374)

The Mouse Monoclonal anti-TSG101 antibody has been validated for WB, IHC, ELISA, IP, IF, IHC (p), FACS, ICC, IEM and IHC (ff). It is suitable to detect TSG101 in samples from Human.
Catalog No. ABIN7469107

Quick Overview for TSG101 antibody (AA 167-374) (ABIN7469107)

Target

See all TSG101 Antibodies
TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivity

  • 77
  • 43
  • 32
  • 11
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  • 9
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  • 8
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  • 5
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Human

Host

  • 68
  • 14
Mouse

Clonality

  • 57
  • 25
Monoclonal

Conjugate

  • 57
  • 4
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  • 2
  • 2
  • 2
  • 2
  • 2
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  • 2
This TSG101 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoelectron Microscopy (IEM), Immunohistochemistry (Free Floating) (IHC (ff))

Grade

KO Validated

Clone

4A10
  • Binding Specificity

    • 9
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 167-374

    Specificity

    Knockdown/Knockout validation was supported by references (PMID:27226592)

    Cross-Reactivity

    Dog, Hamster, Human, Monkey, Mouse, Pig, Rat, Zebrafish (Danio rerio)

    Purification

    Purified by antigen-affinity chromatography.

    Immunogen

    Amino acids 167-374 of TSG101 protein expressed in E. coli.

    Isotype

    IgG1
  • Application Notes

    WB: 1:500-1:3000. ICC/IF: 1:500-1:1000. IHC-P: 1:100-1:1000. FACS: 1:25-1:200. EM: 1:10. IHC: 1:100. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Comment

    Positive Control: 293T , K562 , THP-1 , HL-60 , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , NIH-3T3 , JC , BCL-1 Validation: KO/KD, Orthogonal, Overexpression, Recombinant antibody

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.8 mg/mL

    Buffer

    PBS, No Preservative

    Preservative

    Without preservative

    Storage

    4 °C,-20 °C

    Storage Comment

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    TSG101 (Tumor Susceptibility Gene 101 (TSG101))

    Alternative Name

    tumor susceptibility 101

    Background

    Synonyms: tumor susceptibility 101 , TSG10 , VPS23

    Background: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]

    Molecular Weight

    44 kDa

    Gene ID

    7251

    UniProt

    Q99816
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