FBLN3 antibody

Catalog No. ABIN7469336

This anti-FBLN3 antibody is a Rabbit Polyclonal antibody detecting FBLN3 in WB and IHC (p). Suitable for Human.

Quick Overview for FBLN3 antibody (ABIN7469336)

Target: FBLN3 (Fibulin 3 (FBLN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBLN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: KO Validated

Product Details anti-FBLN3 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human EFEMP1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse liver , Rat liver Validation: KO/KD, Orthogonal, Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.22 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FBLN3

Target: FBLN3 (Fibulin 3 (FBLN3))

Alternative Name: EFEMP1

Background:

Synonyms: EGF containing fibulin extracellular matrix protein 1 , DHRD , DRAD , FBLN3 , FBNL , FIBL-3 , MLVT , MTLV , S1-5

Background: This gene spans approximately 18 kb of genomic DNA and consists of 12 exons. Alternative splice patterns in the 5' UTR result in three transcript variants encoding the same extracellular matrix protein. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. [provided by RefSeq]

Molecular Weight: 55 kDa

Gene ID: 2202

UniProt: Q12805

Pathways: EGFR Signaling Pathway