HEYL antibody

Catalog No. ABIN7469396

This anti-HEYL antibody is a Rabbit Polyclonal antibody detecting HEYL in WB, IF and ICC. Suitable for Human.

Quick Overview for HEYL antibody (ABIN7469396)

Target: HEYL (Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEYL antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-HEYL Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human HEYL. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.31 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HEYL

Target: HEYL (Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL))

Alternative Name: HEYL

Background:

Synonyms: hes related family bHLH transcription factor with YRPW motif like , HESR3 , HEY3 , HRT3 , bHLHb33

Background: This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq]

Molecular Weight: 35 kDa

Gene ID: 26508

UniProt: Q9NQ87

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling