CD5 antibody
Quick Overview for CD5 antibody (ABIN7478849)
Target
See all CD5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Cross-Reactivity (Details)
- Human
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Characteristics
- The antibody to CD5 is used for the classification of lymphoid neoplasm. CD5 is exprimed by the majority of T-cell lymphoma and is also found on B-cells in some cases of chronic lymphatic leukaemia and centrocytic lymphoma. Normally it is not found in other forms of lymphoid neoplasm e.g. follicular lymphoma, Hairy Cell Lymphoma and Large Cell Lymphoma. CD5 is a lymphocyte surface molecule with a molecular weight of 67 kDa. It is exprimed by 95 % of thymocytes and app. 72 % of peripheral blood lymphocytes. In lymph nodes the antigen is detected in the T-cell region mainly. CD5 is over-expressed in leukaemia and T-cell lymphoma and may also be detected in a subpopulation of activated B-cells. Human CD5 Molecule.
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Purification
- Antibody solution
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Immunogen
- Synthetic Protein, corresponding to a sequence of human CD5 molecule
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Isotype
- IgG
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Application Notes
- Paraffin sections are pre-treated with 1 mM EDTA ( pH 8.0) in an autoclave (2 min under full pressure, cooling 15-20 min.),Tonsil,IHC(C, P), FACS,60 min at RT,(liquid conc.) 1:10-1:25
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Restrictions
- For Research Use only
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Buffer
- Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 μl working solution / test).
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- 2-8°C
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- CD5
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Alternative Name
- CD5
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UniProt
- P06127
Target
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