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Recombinant Trastuzumab antibody

This anti-Trastuzumab antibody is a Mouse Monoclonal antibody detecting Trastuzumab in . Suitable for Human.
Catalog No. ABIN7482306

Quick Overview for Recombinant Trastuzumab antibody (ABIN7482306)

Target

Trastuzumab

Antibody Type

Recombinant Antibody

Reactivity

Human

Host

Mouse

Clonality

Monoclonal

Clone

AY1b
  • Purpose

    Anti-Trastuzumab Antibody (AY1b) (recommended for PK/PD)

    Characteristics

    Anti-idiotypic Antibodies

    Immunogen

    Anti-Trastuzumab Antibody (AY1b) are expressed from human 293 cells (HEK293).
  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Storage

    -20 °C
  • Target

    Trastuzumab

    Background

    Trastuzumab, is a monoclonal antibody used to treat breast cancer. Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein.
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