This anti-Trastuzumab antibody is a Mouse Monoclonal antibody detecting Trastuzumab in . Suitable for Human.
Catalog No. ABIN7482306
Quick Overview for Recombinant Trastuzumab antibody (ABIN7482306)
Target
Trastuzumab
Antibody Type
Recombinant Antibody
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Clone
AY1b
Purpose
Anti-Trastuzumab Antibody (AY1b) (recommended for PK/PD)
Characteristics
Anti-idiotypic Antibodies
Immunogen
Anti-Trastuzumab Antibody (AY1b) are expressed from human 293 cells (HEK293).
Restrictions
For Research Use only
Format
Lyophilized
Storage
-20 °C
Target
Trastuzumab
Background
Trastuzumab, is a monoclonal antibody used to treat breast cancer. Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein.