Recombinant Angiotensin II antibody
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- Target See all Angiotensin II (Ang II) Antibodies
- Angiotensin II (Ang II)
- Antibody Type
- Recombinant Antibody
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Reactivity
- Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Angiotensin II antibody is un-conjugated
- Application
- Please inquire
- Purpose
- Anti-Angiotensin II [KAA8], Mouse IgG1, kappa
- Cross-Reactivity
- Human
- Characteristics
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Original Species of Ab: Mouse
Original Format of Ab: IgG
- Purification
- Protein A affinity purified
- Immunogen
- Angiotensin II
- Clone
- KAA8
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product Ang II Primary Antibody
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- Application Notes
- Angiotensin II is a potent regulator of blood pressure, body fluid and electrolyte homeostasis. It acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone.
- Comment
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This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- Angiotensin II (Ang II)
- Alternative Name
- Angiotensin II (Ang II Products)
- Background
- Octapeptide hormone angiotensin II, AII
- UniProt
- P01019
- Pathways
- JAK-STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
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