CD16 antibody (PE)

Catalog No. ABIN7489566

This Mouse Monoclonal antibody specifically detects CD16 in FACS. It exhibits reactivity toward Human, Rhesus Monkey, Cynomolgus and Baboon.

Quick Overview for CD16 antibody (PE) (ABIN7489566)

Target: CD16

Reactivity: Human, Rhesus Monkey, Cynomolgus, Baboon

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD16 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Grade: GMP Grade (Analyte)

Clone: C-4H1G

Product Details anti-CD16 Antibody (PE)

Purpose: CD16 PE Antibody

Characteristics: Alternative clone name HuNK2, the clone C-4H1G, a mouse monoclonal antibody binds to the 50-65 kDa transmembrane protein of IgG FcγRIII known as CD16, a surface antigen commonly associated with human NK cells. In addition to surface expression on NK cells, CD16 is expressed on activated monocytes, macrophages, neutrophils, and placental trophoblasts in humans. C-4H1G has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils.

Purification: Purified

Purity: >95 %

Immunogen: Human peripheral blood T lymphocytes from a NK-leukemia patient

Isotype: IgG2a, kappa

Application Details

Application Notes: FC: 5 μL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for CD16

Target: CD16

Alternative Name: CD16

Gene ID: 2214

UniProt: Q92835

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process