ITGA5 antibody

Catalog No. ABIN7505938

The Mouse Monoclonal anti-ITGA5 antibody is suitable to detect ITGA5 in samples from Human and Non-Human Primate. It has been validated for FACS, IP and IHC (fro).

Quick Overview for ITGA5 antibody (ABIN7505938)

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Reactivity: Human, Non-Human Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGA5 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: SAM1

Product Details anti-ITGA5 Antibody

Purpose: Anti-Hu CD49e Purified

Characteristics: The mouse monoclonal antibody SAM1 recognizes an extracellular epitope of CD49e (integrin 5 alpha), a transmembrane glycoprotein expressed on thymocytes, early and activated B cells, monocytes, NK cells, dendritic cells, osteoblast and endothelial cells.

Purification: Purified by protein-A affinity chromatography.

Immunogen: U937 cells

Isotype: IgG2b

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Alternative Name: CD49e

Background: Integrin subunit alpha 5,CD49e (VLA5 alpha) is a type I transmembrane glycoprotein of the integrin alpha subclass (intergrin 5 alpha), expressed on thymocytes, early and activated B cells, monocytes, NK cells, dendritic cells, osteoblast and endothelial cells. It binds to RGD sequence in fibronectin and to neural adhesion molecule L1. CD49e interactions are important for maintaining the integrity of the endothelial monolayer, as well as it is involved in monocyte migration, T cell costimulation, regulation of cell survival, and other.,VLA5 alpha, integrin 5 alpha, FNRA

Gene ID: 3678

UniProt: P08648

Pathways: Integrin Complex