TCP1 alpha/CCTA antibody

Catalog No. ABIN7506001

The Mouse Monoclonal anti-TCP1 alpha/CCTA antibody has been validated for WB, IP, ICC and IHC (p). It is suitable to detect TCP1 alpha/CCTA in samples from Human, Mouse and Rat.

Quick Overview for TCP1 alpha/CCTA antibody (ABIN7506001)

Target: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This TCP1 alpha/CCTA antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PANp63-6-1

Product Details anti-TCP1 alpha/CCTA Antibody

Purpose: Anti-p63 Purified

Specificity: The mouse monoclonal antibody PANp63-6.1 recognizes both TAp63, and deltaNp63 form of p63. The target epitope PSHLIR is located within amino acids 261-266 of TAp63, and 167-172 of deltaNp63.

Purification: Purified by protein-A affinity chromatography.

Immunogen: Recombinant full length human p63

Isotype: IgG1

Application Details

Application Notes: Western blotting: Recommended dilution: 1 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for TCP1 alpha/CCTA

Target: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Alternative Name: p63

Background: Tumor protein p63,The p53 family of proteins includes three members, p53, p63, and p73. The protein p63 is encoded by TP63 gene, which gives rise to protein isoforms with different properties and functions due to the presence (TAp63) or absence (deltaNp63) of an N-terminal transactivation domain. Immunohistochemistry of p63 has a clinical relevance for certain tumor types, but investigations have been hampered by a lack of well characterized antibodies that are specific for p63 and do not cross-react with the related p53 and p73 proteins.,TAp63 + deltaNp63, AIS, KET, LMS, NBP, RHS, EEC3, OFC8, SHFM4

Gene ID: 8626

UniProt: Q9H3D4