Interleukin 17a antibody

Catalog No. ABIN7536930

The Mouse Monoclonal anti-Interleukin 17a antibody has been validated for ICFC. It is suitable to detect Interleukin 17a in samples from Mouse.

Quick Overview for Interleukin 17a antibody (ABIN7536930)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Interleukin 17a antibody is un-conjugated

Application: Intracellular Flow Cytometry (ICFC)

Clone: 17F3

Product Details anti-Interleukin 17a Antibody

Purpose: Purified Anti-Mouse IL-17A Antibody [17F3]

Purification: Purified

Isotype: IgG1, kappa

Application Details

Application Notes: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 μg per 10^6 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Comment:

Matching Isotype Control: (ABIN7469768)

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Do not freeze.

Expiry Date: 12 months

Target Details for Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Alternative Name: IL-17A

Background: IL-17A,Interleukin-17A,Il17a,Ctla9,The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-18A?in vivo.

Gene ID: 16171

UniProt: Q62386