CD160 antibody (AA 25-155)

Catalog No. ABIN7539709

The Mouse Monoclonal anti-CD160 antibody has been validated for FACS and ELISA. It is suitable to detect CD160 in samples from Human.

Quick Overview for CD160 antibody (AA 25-155) (ABIN7539709)

Target: CD160

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD160 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Clone: 1D4A4

Product Details anti-CD160 Antibody

Binding Specificity: AA 25-155

Purpose: CD160 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD160 (AA: 25-155) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CD160

Target: CD160

Alternative Name: CD160

Background: CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 Molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.

Molecular Weight: 19.8 kDa

Gene ID: 11126

UniProt: O95971