JAM3 antibody (AA 32-241)

Catalog No. ABIN7539787

The Mouse Monoclonal anti-JAM3 antibody has been validated for WB, ELISA and FACS. It is suitable to detect JAM3 in samples from Human.

Quick Overview for JAM3 antibody (AA 32-241) (ABIN7539787)

Target: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This JAM3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 2A5B6

Product Details anti-JAM3 Antibody

Binding Specificity: AA 32-241

Purpose: JAM3 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human JAM3 (AA: 32-241) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for JAM3

Target: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Alternative Name: JAM3

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.

Molecular Weight: 35 kDa

UniProt: Q9BX67