SARS-CoV-2 Spike antibody (RBD)

Catalog No. ABIN7540676

Supplier Product No.: 200-301-ms8

This Mouse Monoclonal antibody specifically detects SARS-CoV-2 Spike in ELISA. It exhibits reactivity toward SARS Coronavirus-2 (SARS-CoV-2).

Quick Overview for SARS-CoV-2 Spike antibody (RBD) (ABIN7540676)

Target: SARS-CoV-2 Spike

Reactivity: SARS Coronavirus-2 (SARS-CoV-2)

Host: Mouse

Clonality: Monoclonal

Conjugate: This SARS-CoV-2 Spike antibody is un-conjugated

Application: ELISA

Clone: 15C11-A4-H11-G7

Product Details anti-SARS-CoV-2 Spike Antibody

Binding Specificity: RBD

Supplier Product No.: 200-301-ms8

Supplier: Rockland

Purpose: SARS-CoV-2 Spike Protein (RBD) Antibody

Cross-Reactivity (Details): Anti-SARS-CoV-2 Spike (RBD) antibody is directed against SARS Coronavirus 2 Spike protein.

Purification: The product was purified from roller bottle culture by protein A chromatography over SARS CoV-2 Spike resin.

Sterility: Sterile filtered

Immunogen: This protein A purified antibody was produced by repeated immunizations with a synthetic peptide corresponding to an internal region of the SARS Coronavirus Spike Protein within the Receptor Binding Domain (RBD).

Isotype: IgG2b kappa

Application Details

Application Notes: Optional[Neutralization_Dilution]: 1:200,000 - 1:325,000

Comment:

Anti-SARS-CoV-2 Spike protein purified antibody has been tested for use in ELISA and shows reactivity to recombinant SARS COV-2 Receptor Binding Domain.  Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for SARS-CoV-2 Spike

Target: SARS-CoV-2 Spike

Alternative Name: SARS-CoV-2 Spike Protein

Background: Mouse anti-SARS CoV 2 Spike Protein Receptor Binding Domain Antibody, Spike glycoprotein antibody, SARS CoV2 antibody, 2019-nCoV, COVID-19, S glycoprotein, Severe acute respiratory syndrome antibody, Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2),SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2 or COVID-19) is related to SARS-CoV, MERS, and four milder coronaviruses (HKU1, NL63, OC43 and 229E). SARS-CoV-2 is an enveloped positive-strand RNA virus that consists of four structural proteins: spike (S) protein, envelope (E) protein, membrane (M) protein and nucleocapsid (N) protein. The spike protein is the most important surface protein of coronavirus. SARS-CoV-2 has a high affinity binding to human receptor ACE2 (angiotensin-converting enzyme 2) within respiratory epithelial. ACE2 is a membrane-bound aminopeptidase that has a vital role in the cardiovascular and immune systems. Anti-SARS-CoV-2 Spike Protein Antibody is useful for researchers interested in diagnostics and viral research.

UniProt: P0DTC2