Recombinant CD6 antibody

Catalog No. ABIN7542967

This anti-CD6 antibody is a Rabbit Chimeric antibody detecting CD6 in FACS and BP. Suitable for Human.

Quick Overview for Recombinant CD6 antibody (ABIN7542967)

Target: CD6

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This CD6 antibody is un-conjugated

Application: Flow Cytometry (FACS), Blocking Peptide (BP)

Clone: OX-124

Product Details anti-CD6 Antibody

Purpose: Anti-CD6 [OX-124], Rabbit IgG, kappa

Specificity: This antibody recognises the ligand-binding domain of human CD6 (domain 3).

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: This antibody was raised by immunizing BALB/c mice with a fusion protein consisting of human CD6 and rat CD4 domains 3 and 4 (CD6d3CD4d3 + 4) (corrected, see: (Hassan et al., 2019, pmid: 30890626)).

Isotype: IgG kappa

Application Details

Application Notes: This antibody blocks CD6/CD166 interactions, crossreacts well and less well on soluble recombinant rat and mouse CD6 respectively (Santos et al., 2019, pmid: 31162836).

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD6

Target: CD6

Alternative Name: CD6

Background: TP120, CD6 Molecule, OX124

UniProt: P30203