Recombinant GPC1 antibody
Quick Overview for Recombinant GPC1 antibody (ABIN7543424)
Target
See all GPC1 AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Glypican-1 [AbAb-GPC1], Rabbit IgG, kappa
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Specificity
- This antibody binds human glypican-1, which is a cell surface proteoglycan that bears heparan sulfate. This protein is required for skeletal muscle differentiation. Glypican-1 (GPC1) was significantly expressed in serum exosomes of patients with pancreatic cancer and so GPC1 is considered as a tumor marker for pancreatic cancer.
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Characteristics
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Original Species of Ab: Rabbit
Original Format of Ab: IgG
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Purification
- Protein A affinity purified
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Immunogen
- The original antibody was generated by immunizing 6-week-old healthy New Zealand female white rabbits subcutaneously with human glypican-1.
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Isotype
- IgG kappa
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Application Notes
- The binding characterization of this antibody to human glypican-1 was determined using ELISA. The binding of this antibody to human glypican-1 expressed on the surface of human breast cancer cell line MDA-MB-231 was determined using flow cytometry (CN112300283).
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- GPC1 (Glypican 1 (GPC1))
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Alternative Name
- Glypican-1
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Background
- GPC1
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UniProt
- P35052
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Pathways
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation
Target
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