CNN1 antibody (AA 201-297)

Catalog No. ABIN724820

The Rabbit Polyclonal anti-CNN1 antibody has been validated for FACS, WB, ELISA, IHC (p), IF (p), IF (cc) and IHC (fro). It is suitable to detect CNN1 in samples from Human, Rat and Mouse. There are 6+ publications available.

Quick Overview for CNN1 antibody (AA 201-297) (ABIN724820)

Target: CNN1 (Calponin 1 (CNN1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNN1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CNN1 Antibody

Binding Specificity: AA 201-297

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Calponin 1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CNN1 antibody (ABIN724820)

Hayashi, Ichimura, Kasai, Sano, Zharhary, Shiozawa, Yaegashi, Konishi: "Characterization of Leiomyomatoid Angiomatous Neuroendocrine Tumour (LANT)-like Tumour in the Myometrium with Histopathological Examination." in: Anticancer research, Vol. 37, Issue 4, pp. 1765-1772, (2017) (PubMed).

Meng, Tong, Liu, Yu, Zhang, Gao: "Epigallocatechin-3-gallate inhibits growth and induces apoptosis in esophageal cancer cells through the demethylation and reactivation of the p16 gene." in: Oncology letters, Vol. 14, Issue 1, pp. 1152-1156, (2017) (PubMed).

Cai, He, Li, Sun, Lam, Qiao, Qiu: "Regulation of tumorigenesis in oral epithelial cells by defined reprogramming factors Oct4 and Sox2." in: Oncology reports, Vol. 36, Issue 2, pp. 651-8, (2016) (PubMed).

Syedain, Meier, Lahti, Johnson, Tranquillo: "Implantation of completely biological engineered grafts following decellularization into the sheep femoral artery." in: Tissue engineering. Part A, Vol. 20, Issue 11-12, pp. 1726-34, (2014) (PubMed).

Zhao, Li, Katzenellenbogen, Lau, Taylor, Bagchi, Bagchi: "Estrogen-Induced CCN1 is Critical for Establishment of Endometriosis-like Lesions in Mice." in: Molecular endocrinology (Baltimore, Md.), pp. me20141080, (2014) (PubMed).

Du, Wang, Zhao, Li, Kong, Yang, Zhang: "Gradient nanofibrous chitosan/poly ?-caprolactone scaffolds as extracellular microenvironments for vascular tissue engineering." in: Biomaterials, Vol. 33, Issue 3, pp. 762-70, (2011) (PubMed).

Target Details for CNN1

Target: CNN1 (Calponin 1 (CNN1))

Alternative Name: Calponin 1

Background:

Synonyms: SMCC, Sm-Calp, HEL-S-14, Calponin-1, Basic calponin, Calponin H1, smooth muscle, CNN1

Background: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).

Molecular Weight: 34kDa

Gene ID: 1264

UniProt: P51911