TACR3 antibody (AA 151-250)

Catalog No. ABIN725735

The Rabbit Polyclonal anti-TACR3 antibody has been validated for ELISA, IHC (p), FACS, IF (cc), IF (p) and IHC (fro). It is suitable to detect TACR3 in samples from Human, Mouse and Rat. There are 2+ publications available.

Quick Overview for TACR3 antibody (AA 151-250) (ABIN725735)

Target: TACR3 (Tachykinin Receptor 3 (TACR3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TACR3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TACR3 Antibody

Binding Specificity: AA 151-250

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NKR

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TACR3 antibody (ABIN725735)

Obata, Shimo, Okui, Matsumoto, Takada, Takabatake, Kunisada, Ibaragi, Yoshioka, Kishimoto, Nagatsuka, Sasaki: "Role of Neurokinin 3 Receptor Signaling in Oral Squamous Cell Carcinoma." in: Anticancer research, Vol. 37, Issue 11, pp. 6119-6123, (2017) (PubMed).

Obata, Shimo, Okui, Matsumoto, Takada, Takabatake, Kunisada, Ibaragi, Nagatsuka, Sasaki: "Tachykinin Receptor 3 Distribution in Human Oral Squamous Cell Carcinoma." in: Anticancer research, Vol. 36, Issue 12, pp. 6335-6341, (2016) (PubMed).

Target Details for TACR3

Target: TACR3 (Tachykinin Receptor 3 (TACR3))

Alternative Name: Neurokinin B receptor

Background:

Synonyms: NKR, HH11, NK3R, NK-3R, TAC3RL, Neuromedin-K receptor, NK-3 receptor, Neurokinin B receptor, Tachykinin receptor 3, TACR3, TAC3R

Background: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.

Gene ID: 6870

UniProt: P29371

Pathways: Feeding Behaviour