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Recombinant B7-H2 (Prezalumab Biosimilar) antibody

This anti-B7-H2 (Prezalumab Biosimilar) antibody is a Human Monoclonal antibody detecting B7-H2 (Prezalumab Biosimilar) in FACS, BLI, ELISA, Func and SPR. Suitable for Human.
Catalog No. ABIN7581254

Quick Overview for Recombinant B7-H2 (Prezalumab Biosimilar) antibody (ABIN7581254)

Target

B7-H2 (Prezalumab Biosimilar)

Antibody Type

Recombinant Antibody

Reactivity

Human

Host

  • 3
Human

Clonality

  • 3
Monoclonal

Conjugate

  • 2
  • 1
This B7-H2 (Prezalumab Biosimilar) antibody is un-conjugated

Application

Flow Cytometry (FACS), Bio-Layer Interferometry (BLI), ELISA, Functional Studies (Func), Surface Plasmon Resonance (SPR)
  • Expression System

    CHO Cells

    Purpose

    Anti-B7-H2 / ICOSL / CD275 Reference Antibody (prezalumab)

    Sequence

    EVQLVESGGG LVQPGGSLRL SCAASGFTFS SYWMSWVRQA PGKGLEWVAY IKQDGNEKYY VDSVKGRFTI SRDNAKNSLY LQMNSLRAED TAVYYCAREG ILWFGDLPTF WGQGTLVTVS SASTKGPSVF PLAPCSRSTS ESTAALGCLV KDYFPEPVTV SWNSGALTSG VHTFPAVLQS SGLYSLSSVV TVPSSNFGTQ TYTCNVDHKP SNTKVDKTVE RKCCVECPPC PAPPVAGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVQFNWYVD GVEVHNAKTK PREEQFNSTF RVVSVLTVVH QDWLNGKEYK CKVSNKGLPA PIEKTISKTK GQPREPQVYT LPPSREEMTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPMLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGK,DIQMTQSPSS LSASVGDRVT ITCRASQGIS NWLAWYQQKP EKAPKSLIYA ASSLQSGVPS RFSGSGSGTD FTLTISSLQP EDFATYYCQQ YDSYPRTFGQ GTKVEIKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC

    Characteristics

    Anti-B7-H2 / ICOSL / CD275 Reference Antibody (prezalumab) is expressed from CHO. The heavy chain type is huIgG2, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

    Purity

    >95 %

    Isotype

    IgG2SA
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Comment

    Therapeutic Agents by Target and Mechanism: ICOS Ligand inhibitors

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Concentration

    1 mg/mL

    Buffer

    25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2

    Storage

    4 °C,-80 °C

    Storage Comment

    +4°C,-80°C
  • Target

    B7-H2 (Prezalumab Biosimilar)

    Target Type

    Biosimilar

    Molecular Weight

    145.5 kDa

    UniProt

    O75144
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