Recombinant CD79B (Polatuzumab Biosimilar) antibody
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- Target
- CD79B (Polatuzumab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
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Host
-
Human
- Expression System
- CHO Cells
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Clonality
- Monoclonal
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Conjugate
- This CD79B (Polatuzumab Biosimilar) antibody is un-conjugated
- Application
- ELISA, Flow Cytometry (FACS), Surface Plasmon Resonance (SPR), Functional Studies (Func), Bio-Layer Interferometry (BLI)
- Purpose
- Anti-CD79b Reference Antibody (polatuzumab)
- Sequence
- EVQLVESGGG LVQPGGSLRL SCAASGYTFS SYWIEWVRQA PGKGLEWIGE ILPGGGDTNY NEIFKGRATF SADTSKNTAY LQMNSLRAED TAVYYCTRRV PIRLDYWGQG TLVTVSSAST KGPSVFPLAP SSKSTSGGTA ALGCLVKDYF PEPVTVSWNS GALTSGVHTF PAVLQSSGLY SLSSVVTVPS SSLGTQTYIC NVNHKPSNTK VDKKVEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSREEMTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGK,DIQLTQSPSS LSASVGDRVT ITCKASQSVD YEGDSFLNWY QQKPGKAPKL LIYAASNLES GVPSRFSGSG SGTDFTLTIS SLQPEDFATY YCQQSNEDPL TFGQGTKVEI KRTVAAPSVF IFPPSDEQLK SGTASVVCLL NNFYPREAKV QWKVDNALQS GNSQESVTEQ DSKDSTYSLS STLTLSKADY EKHKVYACEV THQGLSSPVT KSFNRGEC
- Characteristics
- Anti-CD79b Reference Antibody (polatuzumab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
- Purity
- >95 %
- Isotype
- IgG1
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
-
Therapeutic Agents by Target and Mechanism: CD79b inhibitors
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- 1 mg/mL
- Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
- Storage
- 4 °C,-80 °C
- Storage Comment
- +4°C,-80°C
-
- Target
- CD79B (Polatuzumab Biosimilar)
- Target Type
- Biosimilar
- Molecular Weight
- 145.5 kDa
- UniProt
- P40259
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