Recombinant FOLR1 (Mirvetuximab Biosimilar) antibody
Reactivity: Human
ELISA, FACS, SPR, Func, BLI
Host: Human
Monoclonal
unconjugated
Recombinant Antibody
-
- Target
- FOLR1 (Mirvetuximab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
-
Host
-
Human
- Expression System
- CHO Cells
-
Clonality
- Monoclonal
-
Conjugate
- This FOLR1 (Mirvetuximab Biosimilar) antibody is un-conjugated
- Application
- ELISA, Flow Cytometry (FACS), Surface Plasmon Resonance (SPR), Functional Studies (Func), Bio-Layer Interferometry (BLI)
- Purpose
- Anti-FOLR1 / FRA Reference Antibody (mirvetuximab)
- Sequence
- QVQLVQSGAE VVKPGASVKI SCKASGYTFT GYFMNWVKQS PGQSLEWIGR IHPYDGDTFY NQKFQGKATL TVDKSSNTAH MELLSLTSED FAVYYCTRYD GSRAMDYWGQ GTTVTVSSAS TKGPSVFPLA PSSKSTSGGT AALGCLVKDY FPEPVTVSWN SGALTSGVHT FPAVLQSSGL YSLSSVVTVP SSSLGTQTYI CNVNHKPSNT KVDKKVEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPG,DIVLTQSPLS LAVSLGQPAI ISCKASQSVS FAGTSLMHWY HQKPGQQPRL LIYRASNLEA GVPDRFSGSG SKTDFTLTIS PVEAEDAATY YCQQSREYPY TFGGGTKLEI KRTVAAPSVF IFPPSDEQLK SGTASVVCLL NNFYPREAKV QWKVDNALQS GNSQESVTEQ DSKDSTYSLS STLTLSKADY EKHKVYACEV THQGLSSPVT KSFNRGEC
- Characteristics
- Anti-FOLR1 Reference Antibody (mirvetuximab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.2 kDa.
- Purity
- >95 %
- Isotype
- IgG1
-
anti-FOLR1 (Mirvetuximab Biosimilar) (Glu239Asp-Mutant), (Met241Leu-Mutant) antibody
Research Grade Reactivity: Human ELISA, FACS Host: Mouse Chimeric unconjugated
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
-
Therapeutic Agents by Target and Mechanism: FOLR1 antagonist
Conditions: Ovarian Cancer
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Concentration
- 1 mg/mL
- Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
- Storage
- 4 °C,-80 °C
- Storage Comment
- +4°C,-80°C
-
- Target
- FOLR1 (Mirvetuximab Biosimilar)
- Target Type
- Biosimilar
- Background
- Synonyms: FOLR1, Folate receptor 1
- Molecular Weight
- 145.2 kDa
- UniProt
- P15328
-
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