Recombinant GPNMB (Glembatumumab Biosimilar) antibody
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- Target
- GPNMB (Glembatumumab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
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Host
-
Human
- Expression System
- CHO Cells
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Clonality
- Monoclonal
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Conjugate
- This GPNMB (Glembatumumab Biosimilar) antibody is un-conjugated
- Application
- ELISA, Flow Cytometry (FACS), Surface Plasmon Resonance (SPR), Functional Studies (Func), Bio-Layer Interferometry (BLI)
- Purpose
- Anti-GPNMB Reference Antibody (glembatumumab)
- Sequence
- QVQLQESGPG LVKPSQTLSL TCTVSGGSIS SFNYYWSWIR HHPGKGLEWI GYIYYSGSTY SNPSLKSRVT ISVDTSKNQF SLTLSSVTAA DTAVYYCARG YNWNYFDYWG QGTLVTVSSA STKGPSVFPL APCSRSTSES TAALGCLVKD YFPEPVTVSW NSGALTSGVH TFPAVLQSSG LYSLSSVVTV PSSNFGTQTY TCNVDHKPSN TKVDKTVERK CCVECPPCPA PPVAGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VQFNWYVDGV EVHNAKTKPR EEQFNSTFRV VSVLTVVHQD WLNGKEYKCK VSNKGLPAPI EKTISKTKGQ PREPQVYTLP PSREEMTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPMLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGK,EIVMTQSPAT LSVSPGERAT LSCRASQSVD NNLVWYQQKP GQAPRLLIYG ASTRATGIPA RFSGSGSGTE FTLTISSLQS EDFAVYYCQQ YNNWPPWTFG QGTKVEIKRT VAAPSVFIFP PSDEQLKSGT ASVVCLLNNF YPREAKVQWK VDNALQSGNS QESVTEQDSK DSTYSLSSTL TLSKADYEKH KVYACEVTHQ GLSSPVTKSF NRGEC
- Characteristics
- Anti-GPNMB Reference Antibody (glembatumumab) is expressed from CHO. The heavy chain type is huIgG2, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
- Purity
- >95 %
- Isotype
- IgG2SA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
-
Therapeutic Agents by Target and Mechanism: GPNMB regulators
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- 1 mg/mL
- Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
- Storage
- 4 °C,-80 °C
- Storage Comment
- +4°C,-80°C
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- Target
- GPNMB (Glembatumumab Biosimilar)
- Target Type
- Biosimilar
- Molecular Weight
- 145.5 kDa
- UniProt
- Q14956
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