Recombinant NOTCH1 (Brontictuzumab Biosimilar) antibody

Catalog No. ABIN7675801

The Human Monoclonal anti-NOTCH1 (Brontictuzumab Biosimilar) antibody has been validated for BLI, ELISA, FACS, Func and SPR. It is suitable to detect NOTCH1 (Brontictuzumab Biosimilar) in samples from Human.

Quick Overview for Recombinant NOTCH1 (Brontictuzumab Biosimilar) antibody (ABIN7675801)

Target: NOTCH1 (Brontictuzumab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Human

Clonality: Monoclonal

Conjugate: This NOTCH1 (Brontictuzumab Biosimilar) antibody is un-conjugated

Application: Bio-Layer Interferometry (BLI), ELISA, Flow Cytometry (FACS), Functional Studies (Func), Surface Plasmon Resonance (SPR)

Product Details anti-NOTCH1 (Brontictuzumab Biosimilar) Antibody

Expression System: CHO Cells

Purpose: Anti-NOTCH1 Reference Antibody (brontictuzumab)

Sequence: QVQLVQSGAE VKKPGASVKI SCKVSGYTLR GYWIEWVRQA PGKGLEWIGQ ILPGTGRTNY NEKFKGRVTM TADTSTDTAY MELSSLRSED TAVYYCARFD GNYGYYAMDY WGQGTTVTVS SASTKGPSVF PLAPCSRSTS ESTAALGCLV KDYFPEPVTV SWNSGALTSG VHTFPAVLQS SGLYSLSSVV TVPSSNFGTQ TYTCNVDHKP SNTKVDKTVE RKCCVECPPC PAPPVAGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVQFNWYVD GVEVHNAKTK PREEQFNSTF RVVSVLTVVH QDWLNGKEYK CKVSNKGLPA PIEKTISKTK GQPREPQVYT LPPSREEMTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPMLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGK,QAVVTQEPSL TVSPGGTVTL TCRSSTGAVT TSNYANWFQQ KPGQAPRTLI GGTNNRAPGV PARFSGSLLG GKAALTLSGA QPEDEAEYYC ALWYSNHWVF GGGTKLTVLG QPKAAPSVTL FPPSSEELQA NKATLVCLVS DFYPGAVTVA WKADGSPVKV GVETTKPSKQ SNNKYAASSY LSLTPEQWKS HRSYSCRVTH EGSTVEKTVA PAECS

Characteristics: Anti-NOTCH1 Reference Antibody (brontictuzumab) is expressed from CHO. The heavy chain type is huIgG2, and the light chain type is hulambda. It has a predicted MW of 145.5 kDa.

Purity: >95 %

Isotype: IgG2SA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Therapeutic Agents by Target and Mechanism: NOTCH1 inhibitors, immunity regulators

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 1 mg/mL

Buffer: 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2

Storage: 4 °C,-80 °C

Storage Comment: +4°C,-80°C

Target Details for NOTCH1 (Brontictuzumab Biosimilar)

Target: NOTCH1 (Brontictuzumab Biosimilar)

Target Type: Biosimilar

Molecular Weight: 145.5 kDa

UniProt: P46531