Big Endothelin 1 (AA 81-212) antibody (HRP)

Catalog No. ABIN726254

The Rabbit Polyclonal anti- antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect in samples from Human.

Quick Overview for Big Endothelin 1 (AA 81-212) antibody (HRP) (ABIN726254)

Target: Big Endothelin 1

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 81-212

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Big endothelin-1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Big Endothelin 1

Alternative Name: Big endothelin-1

Background:

Synonyms: EDN1_HUMAN, Big endothelin 1, EDN 1, EDN1, EDN1 protein, Endothelin1, Endothelin 1, Endothelin-1, ET 1, ET1, OTTHUMP00000039245, PPET1,

Background: Big Endothelin-1 is precursor of endothelin 1. Big endothelin-1 is cleaved to yield endothelin-1 via the activity of an endothelin-converting enzyme (ECE). Big Endothelin-1 can be hydrolyzed by chymase to generate endothelin 1 (1-21) in vitro. Endothelins are endothelium-derived vasoconstrictor peptides.

Gene ID: 1906

UniProt: P05305