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Integrin alpha 1 antibody (Biotin)

This Mouse Monoclonal antibody specifically detects Integrin alpha 1 in IP, FACS and IHC (fro). It exhibits reactivity toward Human and Non-Human Primate.
Catalog No. ABIN7595378

Quick Overview for Integrin alpha 1 antibody (Biotin) (ABIN7595378)

Target

See all Integrin alpha 1 (ITGA1) Antibodies
Integrin alpha 1 (ITGA1)

Reactivity

  • 71
  • 28
  • 14
  • 3
  • 3
Human, Non-Human Primate

Host

  • 62
  • 18
  • 1
  • 1
Mouse

Clonality

  • 67
  • 15
Monoclonal

Conjugate

  • 44
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Integrin alpha 1 antibody is conjugated to Biotin

Application

  • 58
  • 26
  • 24
  • 24
  • 20
  • 14
  • 13
  • 13
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone

TS2-7
  • Purpose

    Anti-Hu CD49a Biotin

    Specificity

    The mouse monoclonal antibody TS2/7 recognizes an extracellular epitope of CD49a, the alpha 1 chain of VLA integrin complex, that serves as an adhesion receptor for collagen IV and laminin 1.

    Purification

    Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

    Immunogen

    human CTL line

    Isotype

    IgG1
  • Application Notes

    Flow cytometry: Recommended dilution: 1-5 μg/mL.

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    Store at 2-8°C. Do not freeze.
  • Target

    Integrin alpha 1 (ITGA1)

    Alternative Name

    CD49a

    Background

    CD49a is the alpha 1 chain of VLA integrin complex (together with CD29, serving as the beta 1 chain), and is expressed on activated T cells, monocytes, NK cells, cultured neuronal cells, melanoma cells, mesenchymal cells (including smooth muscle cells), fibroblasts, hepatocytes, and microvascular endothelium. It binds to collagen IV and laminin 1. It is important for leukocyte migration into tissues. It is upregulated in inflammatory tissues, such as inflammed intestine.

    Gene ID

    3672

    UniProt

    P56199

    Pathways

    EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex
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