CLEC12A antibody (FITC)

Catalog No. ABIN7595380

This anti-CLEC12A antibody is a Mouse Monoclonal antibody detecting CLEC12A in FACS. Suitable for Human.

Quick Overview for CLEC12A antibody (FITC) (ABIN7595380)

Target: CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CLEC12A antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: 50C1

Product Details anti-CLEC12A Antibody (FITC)

Purpose: Anti-Hu CD371 FITC

Specificity: The mouse monoclonal antibody 50C1 recognizes an extracellular epitope of CD371, a type II transmembrane glycoprotein expressed above all on monocytes, macrophages, granulocytes and dendritic cells.

Purification: Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: 293T cells expressing human CD371-Flag

Isotype: IgG2a

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for CLEC12A

Target: CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))

Alternative Name: CD371

Background: CD371, also known as CLEC12A, is a 30 kDa type II transmembrane glycoprotein of the C-type lectin family. Several alternatively spliced isoforms have been described. Using ITIM in its cytoplasmic part, this receptor serves as a negative regulator of CD371-positive cells, mainly granulocytes and monocytes, and is involved in dendritic cell maturation. It is one of markers of myeloid cells, including acute myeloid leukemia.

Gene ID: 160364

UniProt: Q5QGZ9