RPS4X antibody (AA 477-498) (FL490)

Catalog No. ABIN7595455

This anti-RPS4X antibody is a Mouse Monoclonal antibody detecting RPS4X in IHC and ICC. Suitable for Human.

Quick Overview for RPS4X antibody (AA 477-498) (FL490) (ABIN7595455)

Target: RPS4X (Ribosomal Protein S4, X-Linked (RPS4X))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RPS4X antibody is conjugated to FL490

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: K91-36

Product Details anti-RPS4X Antibody (FL490)

Binding Specificity: AA 477-498

Purpose: Anti-WAVE1/SCAR Antibody FL490 Conjugate

Specificity: No off-targets reported

Cross-Reactivity: Human, Mouse, Rat

Characteristics:

Description: Our Anti-WAVE1/SCAR mouse monoclonal primary antibody is produced in-house from hybridoma clone K91/36. It is KO validated, detects human, mouse, and rat WAVE1/SCAR, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our WAVE1/SCAR mouse monoclonal primary antibody from hybridoma clone K91/36. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Synthetic peptide amino acids 477-498 of human Wave1/Wasp family 1(CQVIPASEPKRHPSTLPVISDAR, accession number Q92558)

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for RPS4X

Target: RPS4X (Ribosomal Protein S4, X-Linked (RPS4X))

Alternative Name: SCAR

Background:

Synonyms: Wiskott-Aldrich syndrome protein family member 1 (WASP family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1)

Target Description: Wiskott-Aldrich syndrome protein family member 1, Verprolin Homology Domain-Containing Protein 1, Protein WAVE-1 or SCAR1 is encoded by the gene WASF1 and is a member of the Wiskott-Aldrich syndrome protein (WASP)-family. WAVE1/SCAR is an effector protein which transmits of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. WAVE1/SCAR acts as part of the WAVE complex which is involved in the regulation of actin filament reorganization and membrane ruffling. WAVE1/SCAR is expressed in many tissues including brain, ovary, colon, kidney, pancreas and thymus. Diseases associated with this gene include Wiskott-Aldrich Syndrome and Alacrima, Achalasia, And Mental Retardation Syndrome.

Gene Name Alternatives: WASF1 KIAA0269 SCAR1 WAVE1

Molecular Weight: 75 kDa