LRRC4C antibody (AA 551-640) (FL490)

Catalog No. ABIN7595462

This Mouse Monoclonal antibody specifically detects LRRC4C in IHC and ICC. It exhibits reactivity toward Human.

Quick Overview for LRRC4C antibody (AA 551-640) (FL490) (ABIN7595462)

Target: LRRC4C (Leucine Rich Repeat Containing 4C (LRRC4C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LRRC4C antibody is conjugated to FL490

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N49A-21

Product Details anti-LRRC4C Antibody (FL490)

Binding Specificity: AA 551-640

Purpose: Anti-NGL-1/LRRC4C Antibody FL490 Conjugate

Specificity: No off-targets reported for NGL-2 or NGL-3

Cross-Reactivity: Human, Mouse, Rat

Characteristics:

Description: Our Anti-NGL-1/LRRC4C mouse monoclonal primary antibody is produced in-house from hybridoma clone N49A/21. It detects human, mouse, and rat NGL-1/LRRC4C, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our NGL-1/LRRC4C mouse monoclonal primary antibody from hybridoma clone N49A/21. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Fusion protein amino acids 551-640 of human NGL-1 (accession number NP_065980) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for LRRC4C

Target: LRRC4C (Leucine Rich Repeat Containing 4C (LRRC4C))

Alternative Name: LRRC4C

Background:

Synonyms: Leucine-rich repeat-containing protein 4C (Netrin-G1 ligand) (NGL-1)

Target Description: Leucine Rich Repeat Containing 4C is encoded by the gene LRRC4C. LRRC4C may promote neurite outgrowth of developing thalamic neurons. LRRC4C is expressed in the brain. Diseases associated with LRRC4C include Extragonadal Seminoma and Chief Cell Adenoma.

Gene Name Alternatives: LRRC4C KIAA1580 NGL1 UNQ292/PRO331

Molecular Weight: 100 kDa

Pathways: Synaptic Membrane