LRRC4B antibody (AA 598-709) (FL490)

Catalog No. ABIN7595465

This Mouse Monoclonal antibody specifically detects LRRC4B in IHC and ICC. It exhibits reactivity toward Rat.

Quick Overview for LRRC4B antibody (AA 598-709) (FL490) (ABIN7595465)

Target: LRRC4B (Leucine Rich Repeat Containing 4B (LRRC4B))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This LRRC4B antibody is conjugated to FL490

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N51-6

Product Details anti-LRRC4B Antibody (FL490)

Binding Specificity: AA 598-709

Purpose: Anti-NGL-3/LRRC4B Antibody FL490 Conjugate

Specificity: No off-targets reported for NGL-1 or NGL-2

Cross-Reactivity: Mouse, Rat

Characteristics:

Description: Our Anti-NGL-3/LRRC4B mouse monoclonal primary antibody is produced in-house from hybridoma clone N51/6. It detects mouse and rat NGL-3/LRRC4B, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our NGL-3/LRRC4B mouse monoclonal primary antibody from hybridoma clone N51/6. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Fusion protein amino acids 598-709 of rat NGL-3 (Leucine-rich repeat-containing 4B protein (Lrrc4B), accession number XP_218615) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for LRRC4B

Target: LRRC4B (Leucine Rich Repeat Containing 4B (LRRC4B))

Alternative Name: LRRC4B

Background:

Synonyms: Leucine-rich repeat-containing protein 4B (Netrin-G3 ligand) (NGL-3)

Target Description: Leucine Rich Repeat Containing 4B is encoded by the gene LRRC4B. LRRC4B is a synaptic adhesion protein that regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner. LRRC4B is expressed in the brain. No disorders were found to be associated with LRRC4B.

Gene Name Alternatives: Lrrc4b Lrig4

Molecular Weight: 100 kDa

Pathways: Synaptic Membrane