Neuroligin 3 antibody (AA 730-848) (FL490)

Catalog No. ABIN7595502

The Mouse Monoclonal anti-Neuroligin 3 antibody has been validated for IHC and ICC. It is suitable to detect Neuroligin 3 in samples from Rat.

Quick Overview for Neuroligin 3 antibody (AA 730-848) (FL490) (ABIN7595502)

Target: Neuroligin 3 (NLGN3)

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Neuroligin 3 antibody is conjugated to FL490

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N110-29

Product Details anti-Neuroligin 3 Antibody (FL490)

Binding Specificity: AA 730-848

Purpose: Anti-Neuroligin-3 Antibody FL490 Conjugate

Specificity: No off-targets reported for Neuroligin-1, -2, -4 or -4*

Cross-Reactivity: Human, Mouse, Rat

Characteristics:

Description: Our Anti-Neuroligin-3 mouse monoclonal primary antibody is produced in-house from hybridoma clone N110/29. It is KO validated, detects human and mouse Neuroligin-3, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our Neuroligin-3 mouse monoclonal primary antibody from hybridoma clone N110/29. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Fusion protein amino acids 730-848 (intracellular C-terminus) of rat Neuroligin-3 (accession number AAA97871) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for Neuroligin 3

Target: Neuroligin 3 (NLGN3)

Alternative Name: Neuroligin-3

Background:

Synonyms: Neuroligin-3 (Gliotactin homolog)

Target Description: Neuroligin3 is encoded by the gene NLGN3. Neuroligin3 is a transmembrane scaffolding protein and cell adhesion molecule. It is involved in cell-cell interactions in neurons and in other cell types. It is expressed in many tissues, including the brain where it is located at the postysynaptic membrane and is involved in regulation of excitatory synapses, synapse formation and synaptic transmission. Mutations in this gene may be associated with autism and Asperger syndrome.

Gene Name Alternatives: Nlgn3

Molecular Weight: 110 kDa

Pathways: Synaptic Membrane