DLG1 antibody (AA 1-104) (FL490)

Catalog No. ABIN7595518

This anti-DLG1 antibody is a Mouse Monoclonal antibody detecting DLG1 in IHC and ICC. Suitable for Rat.

Quick Overview for DLG1 antibody (AA 1-104) (FL490) (ABIN7595518)

Target: DLG1 (Discs, Large Homolog 1 (DLG1))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This DLG1 antibody is conjugated to FL490

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: K64-15

Product Details anti-DLG1 Antibody (FL490)

Binding Specificity: AA 1-104

Purpose: Anti-SAP97 Antibody FL490 Conjugate

Specificity: No off-targets reported for PSD-95, Chapsyn-110 and SAP102 expressed in transfected cells

Cross-Reactivity: Human, Mouse, Rat

Characteristics:

Description: Our Anti-SAP97 mouse monoclonal primary antibody is produced in-house from hybridoma clone K64/15. It is KO validated, detects human, mouse, and rat SAP97, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our SAP97 mouse monoclonal primary antibody from hybridoma clone K64/15. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Fusion protein amino acids 1-104 (N-terminus) of rat SAP97 (accession number Q62696) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for DLG1

Target: DLG1 (Discs, Large Homolog 1 (DLG1))

Alternative Name: SAP97

Background:

Synonyms: Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)

Target Description: Synapse-associated protein 97, Discs Large MAGUK Scaffold Protein 1 or SAP97 is encoded by the gene DLG1. SAP97 is a member of the MAGUK (membrane-associated guanylate kinase) protein family. It is a multi-domain scaffolding protein which serves to recruit receptors channels and other signaling molecules to the plasma membrane. SAP97 is expressed in heart, lung, epithelial cells and brain. SAP97 may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Diseases associated with DLG1 include Mayer-Rokitansky-Kuster-Hauser Syndrome and Depression.

Gene Name Alternatives: Dlg1 Dlgh1

Molecular Weight: 130 kDa

Pathways: Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response