SLC38A1 antibody (AA 1-63) (FL550)

Catalog No. ABIN7595653

This anti-SLC38A1 antibody is a Mouse Monoclonal antibody detecting SLC38A1 in ICC. Suitable for Rat.

Quick Overview for SLC38A1 antibody (AA 1-63) (FL550) (ABIN7595653)

Target: SLC38A1 (Solute Carrier Family 38 Member 1 (SLC38A1))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLC38A1 antibody is conjugated to FL550

Application: Immunocytochemistry (ICC)

Clone: N104-37

Product Details anti-SLC38A1 Antibody (FL550)

Binding Specificity: AA 1-63

Purpose: Anti-SNAT1 Antibody FL550 Conjugate

Specificity: No off-targets reported

Cross-Reactivity: Human, Mouse, Rat

Characteristics:

Description: Our Anti-SNAT1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N104/37. It detects human, mouse, and rat SNAT1, and is purified by Protein A chromatography. It is great for use in ICC.

Manufacturer Comment: We produce our SNAT1 mouse monoclonal primary antibody from hybridoma clone N104/37. It is great in ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Fusion protein amino acids 1-63 (cytoplasmic N-terminus) of rat SNAT1 (accession number Q9JM15) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for SLC38A1

Target: SLC38A1 (Solute Carrier Family 38 Member 1 (SLC38A1))

Alternative Name: SNAT1

Background:

Synonyms: Sodium-coupled neutral amino acid transporter 1 (Amino acid transporter A1) (rATA1) (Glutamine transporter) (N-system amino acid transporter 2) (Solute carrier family 38 member 1) (System A amino acid transporter 1) (System A transporter 2) (System N amino acid transporter 1)

Target Description: Sodium-coupled neutral amino acid transporter 1 (SNAT1) or Solute Carrier Family 38 Member 1 is encoded by the gene Slc38a1 and belongs to the amino acid/polyamine transporter 2 family. SNAT1 acts as a sodium-dependent transporter of glutamine which serves as a precursor for the synaptic transmitter, glutamate. SNAT1 is expressed in brain, specifically at glutamatergic and GABAergic neurons, and also expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis. Diseases associated with this gene include Klatskin's Tumor.

Gene Name Alternatives: Slc38a1 Ata1 Glnt Sa2 Sat1 Snat1

Molecular Weight: 50 kDa