MPHOSPH8 antibody (AA 50-120) (FL594)

Catalog No. ABIN7595720

Product Details anti-MPHOSPH8 Antibody (FL594)

Target: MPHOSPH8 (M-Phase phosphoprotein 8 (MPHOSPH8))

Binding Specificity: AA 50-120

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MPHOSPH8 antibody is conjugated to FL594

Application: Immunocytochemistry (ICC)

Purpose: Anti-MPP8 Antibody FL594 Conjugate

Specificity: No off-targets reported

Cross-Reactivity: Human

Characteristics:

Description: Our Anti-MPP8 mouse monoclonal primary antibody is produced in-house from hybridoma clone N119/44. It detects human MPP8, and is purified by Protein A chromatography. It is great for use in ICC.

Manufacturer Comment: We produce our MPP8 mouse monoclonal primary antibody from hybridoma clone N119/44. It is great in ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Fusion protein amino acids 50-120 (Chromo domain) of human MPP8 (accession number Q99549) produced recombinantly in E. Coli

Clone: N119-44

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for MPHOSPH8

Target: MPHOSPH8 (M-Phase phosphoprotein 8 (MPHOSPH8))

Alternative Name: MPP8 (MPHOSPH8 Products)

Background:

Synonyms: M-phase phosphoprotein 8 (Two hybrid-associated protein 3 with RanBPM) (Twa3)

Target Description: M-Phase Phosphoprotein 8 is encoded by the gene MPHOSPH8. MPHOSPH8 is a heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression. MPHOSPH8 is expressed in the brain. Diseases associated with MPHOSPH8 include Charcot-Marie-Tooth Disease.

Gene Name Alternatives: MPHOSPH8 MPP8

Molecular Weight: 100 kDa