LRRC4 antibody (AA 550-652) (FL594)

Catalog No. ABIN7595725

This anti-LRRC4 antibody is a Mouse Monoclonal antibody detecting LRRC4 in IHC and ICC. Suitable for Mouse.

Quick Overview for LRRC4 antibody (AA 550-652) (FL594) (ABIN7595725)

Target: LRRC4 (Leucine Rich Repeat Containing 4 (LRRC4))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This LRRC4 antibody is conjugated to FL594

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N50-36

Product Details anti-LRRC4 Antibody (FL594)

Binding Specificity: AA 550-652

Purpose: Anti-NGL-2/LRRC4 Antibody FL594 Conjugate

Specificity: No off-targets reported for NGL-1 or NGL-3

Cross-Reactivity: Mouse, Rat

Characteristics:

Description: Our Anti-NGL-2/LRRC4 mouse monoclonal primary antibody is produced in-house from hybridoma clone N50/36. It is KO validated, detects mouse and rat NGL-2/LRRC4, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our NGL-2/LRRC4 mouse monoclonal primary antibody from hybridoma clone N50/36. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Fusion protein amino acids 550-652 of mouse NGL-2 (accession number AAG60620) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for LRRC4

Target: LRRC4 (Leucine Rich Repeat Containing 4 (LRRC4))

Alternative Name: LRRC4

Background:

Synonyms: Leucine-rich repeat-containing protein 4 (Brain tumor-associated protein MBAG1) (Netrin-G2 ligand) (NGL-2)

Target Description: Leucine Rich Repeat Containing 4 is encoded by the gene LRRC4. LRRC4 is a synaptic adhesion protein that regulates the formation of excitatory synapses through the recruitment of pre and postsynaptic proteins. LRRC4 organizes the lamina pathway-specific differentiation of dendrites, and plays an important role in auditory synaptic responses. LRRC4 is expressed in the brain. LRRC4 is significantly downregulated in primary brain tumors.

Gene Name Alternatives: Lrrc4

Molecular Weight: 100 kDa

Pathways: Synaptic Membrane