Neuroligin 4 antibody (AA 782-945) (FL594)

Catalog No. ABIN7595773

This anti-Neuroligin 4 antibody is a Mouse Monoclonal antibody detecting Neuroligin 4 in ICC. Suitable for Mouse.

Quick Overview for Neuroligin 4 antibody (AA 782-945) (FL594) (ABIN7595773)

Target: Neuroligin 4 (NLGN4)

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Neuroligin 4 antibody is conjugated to FL594

Application: Immunocytochemistry (ICC)

Clone: N98-47

Product Details anti-Neuroligin 4 Antibody (FL594)

Binding Specificity: AA 782-945

Purpose: Anti-Neuroligin-4* Antibody FL594 Conjugate

Specificity: No off-targets reported for other Neuroligins

Cross-Reactivity: Mouse

Characteristics:

Description: Our Anti-Neuroligin-4* mouse monoclonal primary antibody is produced in-house from hybridoma clone N98/47. It detects mouse Neuroligin-4*, and is purified by Protein A chromatography. It is great for use in ICC.

Manufacturer Comment: We produce our Neuroligin-4* mouse monoclonal primary antibody from hybridoma clone N98/47. It is great in ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Fusion protein amino acids 782-945 (intracellular C-terminus) of mouse Neuroligin-4* (accession number ABS19580) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for Neuroligin 4

Target: Neuroligin 4 (NLGN4)

Alternative Name: Neuroligin-4*

Background:

Synonyms: Neuroligin 4-like (Neuroligin-4) (NL-4)

Target Description: Neuroligin4 is encoded by the gene NLGN4. Neuroligin4 is a transmembrane scaffolding protein and cell adhesion molecule. It is involved in cell-cell interactions in neurons and in other cell types. It is expressed in many tissues, including retina and brain, where it is located at the postysynaptic membrane and is involved in regulation of synapses, synapse formation and synaptic transmission. Diseases associated with this gene include forms of Autism and Asperger Syndrome.

Gene Name Alternatives: Nlgn4l Nl4* Nlgn4 Nlgn4x

Molecular Weight: 125-130 kDa

Pathways: Cell-Cell Junction Organization, Synaptic Membrane