SNAPIN antibody (AA 115-136) (FL650)

Catalog No. ABIN7595821

This anti-SNAPIN antibody is a Mouse Monoclonal antibody detecting SNAPIN in IHC and ICC. Suitable for Human.

Quick Overview for SNAPIN antibody (AA 115-136) (FL650) (ABIN7595821)

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SNAPIN antibody is conjugated to FL650

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: L8-15

Product Details anti-SNAPIN Antibody (FL650)

Binding Specificity: AA 115-136

Purpose: Anti-Snapin/SNAPAP Antibody FL650 Conjugate

Specificity: No off-targets reported

Cross-Reactivity: Human, Mouse, Rat

Characteristics:

Description: Our Anti-Snapin/SNAPAP mouse monoclonal primary antibody is produced in-house from hybridoma clone L8/15. It detects human, mouse, and rat Snapin/SNAPAP, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our Snapin/SNAPAP mouse monoclonal primary antibody from hybridoma clone L8/15. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Synthetic peptide of amino acids 115-136 of human snapin (KETARRRAMLDSGIYPPGSPGK, accession number Q95295)

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for SNAPIN

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Alternative Name: SNAPAP

Background:

Synonyms: SNARE-associated protein Snapin (Biogenesis of lysosome-related organelles complex 1 subunit 7) (BLOC-1 subunit 7) (Synaptosomal-associated protein 25-binding protein) (SNAP-associated protein)

Target Description: SNARE-associated protein Snapin, SNAP Associated Protein or Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 7 (BLOC-1 Subunit 7) is encoded by the gene SNAPIN. Snapin is a member of the BLOC-1 complex, which is involved in the protein-sorting, membrane biogenesis, and vesicular trafficking. Snapin is required for vesicle docking and fusion and regulates neurotransmitter release. Snapin is expressed in many tissues including heart, brain, testis, kidney and liver. Diseases associated with this gene include Hermansky-Pudlak Syndrome and Tricuspid Valve Stenosis.

Gene Name Alternatives: SNAPIN BLOC1S7 SNAP25BP SNAPAP

Molecular Weight: 20 kDa

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis