CNTNAP1 antibody (Cytoplasmic Domain)

Catalog No. ABIN7595948

This Mouse Monoclonal antibody specifically detects CNTNAP1 in WB, IHC and IP. It exhibits reactivity toward Rat.

Quick Overview for CNTNAP1 antibody (Cytoplasmic Domain) (ABIN7595948)

Target: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CNTNAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: K65-35

Product Details anti-CNTNAP1 Antibody

Binding Specificity: Cytoplasmic Domain

Purpose: Anti-CASPR/Neurexin IV Antibody

Specificity: No off-targets reported

Cross-Reactivity: Gerbil, Human, Mouse, Rat

Characteristics:

Description: Our Anti-CASPR/Neurexin IV mouse monoclonal primary antibody is produced in-house from hybridoma clone K65/35. It is KO validated, detects gerbil, human, mouse, and rat CASPR/Neurexin IV, and is purified by Protein A chromatography. It is great for use in IHC, IP, WB.

Manufacturer Comment: We produce our CASPR/Neurexin IV mouse monoclonal primary antibody from hybridoma clone K65/35. It is great in IHC, IP, WB and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Purity: > 90 % specific antibody

Immunogen: Fusion protein 1308-1381 (cytoplasmic domain) of rat Caspr (accession number P97846) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes:

Dilution Range: IHC: 1:250

Dilution Range: ICC: 1:500

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 24 months

Target Details for CNTNAP1

Target: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Alternative Name: Neurexin IV

Background:

Synonyms: Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (Paranodin) (p190)

Target Description: CASPR (Neurexin IV) is part of the neurexin family, which includes presynaptic proteins located in the presynaptic membrane of the brain.

Gene Name Alternatives: Cntnap1 Caspr Nrxn4

Molecular Weight: 220 kDa

Pathways: Cell-Cell Junction Organization