hTSH antibody (Biotin)
Quick Overview for hTSH antibody (Biotin) (ABIN7596008)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Purpose
- Anti-hTSH Biotin
-
Specificity
- The antibody TSH-51 reacts with human thyroid stimulating hormone (hTSH, thyrotropin), a glycoprotein hormone produced by the anterior pituitary gland cells in response to signals from the hypothalamus gland in the brain. The TSH-51 antibody reacts with association constant 5.5 x 1010 l/mol. Following cross-reactivity expressed as binding of labelled hormone (% of total) was determined by solid phase RIA with excess of the antibody TSH-51: hTSH (68.6), hCG (0.03), hLH (2.99), hFSH (0.66).
-
Purification
- Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
-
Immunogen
- Human thyrotropin.
-
Isotype
- IgG2a
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1 mg/mL
-
Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C
-
Storage Comment
- Store at 2-8°C. Do not freeze.
-
-
- hTSH
-
Background
- Thyrotropin (hTSH) promotes the growth of the thyroid gland in the neck and stimulates it to produce more thyroid hormones. hTSH is composed of two subunits - alpha nad beta.,Thyrotropin
-
Gene ID
- 35
Target
-