This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C,-80 °C
Storage Comment
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Target
STEAP1
(Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))
Alternative Name
STEAP1
Background
Six-transmembrane epithelial antigen of the prostate (STEAP) is expressed predominantly in human prostatetissue and in other common malignancies including prostate, bladder, colon, and ovarian carcinomas, and in Ewing's sarcoma, suggesting that it could function as an almost universal tumor antigen. Immunohistochemical analysisindicated STEAP-1 localization at cell-cell junctions of the secretory epithelium of prostate and prostatecancer cells. The favorable expression profiling of STEAP-1 in normal and cancer tissues suggested itspotential use as a target for immunotherapy.