MEMO1 antibody (AA 1-297)

Catalog No. ABIN7596069

This Mouse Monoclonal antibody specifically detects MEMO1 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for MEMO1 antibody (AA 1-297) (ABIN7596069)

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MEMO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: AT1E9

Product Details anti-MEMO1 Antibody

Binding Specificity: AA 1-297

Purpose: Human MEMO1 antibody

Purification: protein-A affinity chromatography

Immunogen: Recombinant human MEMO1 (1-297aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for MEMO1

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Alternative Name: MEMO1

Background: MEMO1 (Mediator of ErbB2-driven cell motility 1) is a 297 amino acid protein. It is thought to relax extracellular chemotactic signals that are targeted at the microtubule cytoskeleton, thereby controlling cell migration. Additionally, MEMO1 is required for breast carcinoma migration, suggesting an important role in tumorigenesis. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity.

NCBI Accession: NP_057039