TOLLIP antibody (AA 61-274)

Catalog No. ABIN7596071

This anti-TOLLIP antibody is a Mouse Monoclonal antibody detecting TOLLIP in WB and ELISA. Suitable for Human.

Quick Overview for TOLLIP antibody (AA 61-274) (ABIN7596071)

Target: TOLLIP (Toll Interacting Protein (TOLLIP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TOLLIP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: K1B17

Product Details anti-TOLLIP Antibody

Binding Specificity: AA 61-274

Purpose: Human Tollip antibody

Purification: Purified

Immunogen: Recombinant human Tollip (61-274aa) purified from E. coli

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for TOLLIP

Target: TOLLIP (Toll Interacting Protein (TOLLIP))

Alternative Name: Tollip

Background: Toll interacting protein, also known as Tollip, is an inhibitory adaptor protein within the signaling pathwayof IL-1 and Toll-like receptors (TLR). The Toll-like receptors are essential transmembrane signalingreceptors of the innate immune system that alert the host to the presence of a microbial invader. Tolliprecruits IRAk1 to the IL-1 receptor complex and inhibits IRAk1 phosphorylation and kinase activity.

NCBI Accession: NP_061882