Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PARD3 antibody (AA 1-1346)

The Rabbit Polyclonal anti-PARD3 antibody has been validated for WB, ELISA, IHC, IF, FACS and ICC. It is suitable to detect PARD3 in samples from Human.
Catalog No. ABIN7598983

Quick Overview for PARD3 antibody (AA 1-1346) (ABIN7598983)

Target

See all PARD3 Antibodies
PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Reactivity

  • 57
  • 25
  • 17
  • 3
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 55
  • 3
Rabbit

Clonality

  • 57
  • 1
Polyclonal

Conjugate

  • 27
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PARD3 antibody is un-conjugated

Application

  • 44
  • 25
  • 13
  • 13
  • 13
  • 10
  • 6
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
  • Binding Specificity

    • 15
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-1346

    Purpose

    Anti-PAR-3/PARD3 Antibody Picoband®

    Cross-Reactivity (Details)

    No cross-reactivity with other proteins.

    Characteristics

    Anti-PAR-3/PARD3 Antibody Picoband® (ABIN7598983). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human PAR-3/PARD3 recombinant protein (Position: M1-Q1346).

    Isotype

    IgG
  • Application Notes

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Chan, J. R., Jolicoeur, C., Yamauchi, J., Elliott, J., Fawcett, J. P., Ng, B. K., Cayouette, M. The polarity protein Par-3 ly interacts with p75(NTR) to regulate myelination. Science 314: 832-836, 2006. 2. Chen, X., An, Y., Gao, Y., Guo, L., Rui, L., Xie, H., Sun, M., Lam Hung, S., Sheng, X., Zou, J., Bao, Y., Guan, H., Niu, B., Li, Z., Finnell, R. H., Gusella, J. F., Wu, B.-L., Zhang, T. Rare deleterious PARD3 variants in the aPKC-binding region are implicated in the pathogenesis of human cranial neural tube defects via disrupting apical tight junction formation. Hum. Mutat. 38: 378-389, 2017. 3. Coureuil, M., Mikaty, G., Miller, F., Lecuyer, H., Bernard, C., Bourdoulous, S., Dumenil, G., Mege, R.-M., Weksler, B. B., Romero, I. A., Couraud, P.-O., Nassif, X. Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium. Science 325: 83-87, 2009.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Storage

    4 °C,-20 °C

    Storage Comment

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

    Alternative Name

    PARD3

    Background

    Synonyms: C-C chemokine receptor type 1,C-C CKR-1,CC-CKR-1,CCR-1,CCR1,Macrophage inflammatory protein 1-alpha receptor,MIP-1alpha-R,RANTES-R,CD191,Ccr1,Cmkbr1,

    Tissue Specificity: Detected in the heart, spleen, lung, peritoneal exudate cells and leukocytes.

    Background: Partitioning defective 3 homolog is a protein that in humans is encoded by the PARD3 gene. This gene encodes a member of the PARD protein family. PARD family members interact with other PARD family members and other proteins, they affect asymmetrical cell division and polarized cell growth. Multiple alternatively spliced transcript variants have been described for this gene.

    Molecular Weight

    151 kDa

    Gene ID

    56288

    Pathways

    Cell-Cell Junction Organization
You are here:
Chat with us!