RPS17 antibody (AA 1-135)

Catalog No. ABIN7598984

This anti-RPS17 antibody is a Rabbit Polyclonal antibody detecting RPS17 in WB, ELISA, IF, FACS and ICC. Suitable for Human, Mouse and Rat.

Quick Overview for RPS17 antibody (AA 1-135) (ABIN7598984)

Target: RPS17 (Ribosomal Protein S17 (RPS17))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Product Details anti-RPS17 Antibody

Binding Specificity: AA 1-135

Purpose: Anti-RPS17 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-RPS17 Antibody Picoband® (ABIN7598984). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RPS17 recombinant protein (Position: M1-V135).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chen, I.-T., Dixit, A., Rhoads, D. D., Roufa, D. J. Homologous ribosomal proteins in bacteria, yeast, and humans. Proc. Nat. Acad. Sci. 83: 6907-6911, 1986. 2. Chen, I.-T., Roufa, D. J. The transcriptionally active human ribosomal protein S17 gene. Gene 70: 107-116, 1988. 3. Cmejla, R., Cmejlova, J., Handrkova, H., Petrak, J., Pospisilova, D. Ribosomal protein S17 gene (RPS17) is mutated in Diamond-Blackfan anemia. Hum. Mutat. 28: 1178-1182, 2007.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for RPS17

Target: RPS17 (Ribosomal Protein S17 (RPS17))

Alternative Name: RPS17

Background:

Synonyms: T-lymphocyte surface antigen Ly-9, Cell surface molecule Ly-9, Lymphocyte antigen 9, SLAM family member 3, SLAMF3, Signaling lymphocytic activation molecule 3, CD229, LY9, CDABP0070

Tissue Specificity: Increased surface expression on T-cells of systemic lupus erythematosus (SLE) patients.

Background: 40S ribosomal protein S17 is a protein that in humans is encoded by the RPS17 gene. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17E family of ribosomal proteins and is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia 4. Alternative splicing of this gene results in multiple transcript variants. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Molecular Weight: 18 kDa

Gene ID: 6218

UniProt: P08708

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly