ACP1 antibody (AA 1-158)

Catalog No. ABIN7599015

This Rabbit Polyclonal antibody specifically detects ACP1 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for ACP1 antibody (AA 1-158) (ABIN7599015)

Target: ACP1 (Acid Phosphatase 1, Soluble (ACP1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ACP1 Antibody

Binding Specificity: AA 1-158

Purpose: Anti-Acid phosphatase/ACP1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Acid phosphatase/ACP1 Antibody Picoband® (ABIN7599015). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Acid phosphatase/ACP1 recombinant protein (Position: M1-H158).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Arnaud, J., Vavrusa, B., Sevin, J., Constans, J. Human red-cell acid phosphatase (ACP1): a new mutant (ACP1*KUK) detected by isoelectric focusing, kinetics of thermostability and substrate activity. Hum. Hered. 39: 288-293, 1989. 2. Arnaud, J., Vavrusa, B., Wiederanders, G., Constans, J. Human red-cell acid phosphatase (ACP1): kinetic and thermodynamic characterization of the KUK variant. Hum. Hered. 42: 140-142, 1992. 3. Beemer, F. A., van der Heiden, C., Van Hemel, J. O., Jansen, M. Letter to the editors. (Letter) Clin. Genet. 24: 151, 1983.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for ACP1

Target: ACP1 (Acid Phosphatase 1, Soluble (ACP1))

Alternative Name: ACP1

Background:

Synonyms: Platelet-activating factor acetylhydrolase, PAF acetylhydrolase, 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, Group-VIIA phospholipase A2, gVIIA-PLA2, LDL-associated phospholipase A2, LDL-PLA (2), PAF 2-acylhydrolase, PLA2G7, PAFAH

Tissue Specificity: Plasma.

Background: Low molecular weight phosphotyrosine protein phosphatase is an enzyme that in humans is encoded by the ACP1 gene. The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Molecular Weight: 17 kDa

Gene ID: 52

UniProt: P24666